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Comparative study of the effects of intense pulse light and traditional massage on the subcutaneous nerve plexus and dendritic cells in the cornea of MGD patients

Comparative study of the effects of intense pulse light and traditional massage on the subcutaneous nerve plexus and dendritic cells in the cornea of MGD patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014775
Enrollment
Unknown
Registered
2018-02-04
Start date
2018-02-15
Completion date
Unknown
Last updated
2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meibomian gland dysfunction

Interventions

OPT group:intense pulse light treatment
traditional massage group: hot compress and massage treatment

Sponsors

Shandong Eye Instiute, Qingdao Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The adult subjects who were diagnosed with MGD (>stage1, according to the 2011 International Workshop on MGD1) and had not conducted eyelid hygiene or undergone any alternative treatments for at least 3 months, were enrolled consecutively in the study. Diagnostic criteria: 1. symptoms of ocular discomfort, such as eye irritation that limited activities; 2. clinical signs: meibum quality grade =4 or MG expressibility =1.

Exclusion criteria

Exclusion criteria: 1. previous ocular surgery or trauma (excluding chalazion section); 2. blepharal dysraphism; 3. a history of blepharal and periorbital skin disease in 1 month; 4. acute inflammation.

Design outcomes

Primary

MeasureTime frame
Meibomian gland score;Schirmer test;Corneal conjunctival staining score;Confocal microscopy;

Countries

China

Contacts

Public ContactJun Cheng

Shandong Eye Instiute, Qingdao Eye Hospital

alice.567@163.com+86 18653280868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026