DIURNAL MOUTHPIECE VENTILTION AND NOCTURNAL NON INVASIVE VENTILATION VERSUS INVASIVE MECHANICAL VENTILATION IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800014772

Enrollment

Unknown

Registered

2018-02-04

Start date

2005-01-01

Completion date

Unknown

Last updated

2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

amyotrophic lateral sclerosis

Interventions

Mouthpiece:Mouthpiece + nocturnal non invasive ventilation

Tracheostomy:Invasive ventilation

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients with amyotrophic lateral sclerosis and ventilatory insufficiency (FVC in supine position less than 50% ) o sleep nocturnal respiratory disturbance

Exclusion criteria

Exclusion criteria: Other neuromuscular disorders; Absence of written informed consense.

Design outcomes

Primary

Measure	Time frame
Mortality;	—

Contacts

Public ContactNicolini Antonello

Respiratory dieaeses unit hospital of sestri levante

antonellonicolini@alice.it+390185329145

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026