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The predictive value of pharmacogenomic testing in treatment of chronic cough

Effect and mechanism of P2X receptors mediated by TRPV4 and ATP on cough hypersensitivity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014768
Enrollment
Unknown
Registered
2018-02-03
Start date
2018-03-01
Completion date
Unknown
Last updated
2018-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic cough

Interventions

Case series:Nil

Sponsors

Tongji Hospital, Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years old; 2. Cough duration>8weeks; 3. No fever,hemoptysis,wheezing,etc, No rales in the lungs, General treatment,including antibiotics,is ineffective; 4. The chest radiograph showed no abnormalities; 5. Pulmonary function test: FEV1/FVC=70%, FEV1>80% of the expected value.

Exclusion criteria

Exclusion criteria: 1. Chronic cough patients with two or more causes of chronic cough; 2. unexplained chronic cough patients 3. Lost follow-up.

Design outcomes

Primary

MeasureTime frame
pharmacogenomic testing;Cough symptom score;Capsaicin cough susceptibility test;—

Countries

China

Contacts

Public ContactXianghuai Xu

Department of clincial laboratory, Shanghai Tongji hospital

05849@tongji.edu.cn+86 13764459488

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026