Depression and chronic pain
Conditions
Interventions
Sponsors
Li Sheng
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Participants will include if they meeting the following criteria: 1. Meet the criteria of DSM-5TM(18) and ICD-10 (19)for the mild-moderate depression; 2. The total score of the 17-item Hamilton Depression Rating Scale (HAMD-17) <23 and =8. 3. The chronic pain persist more than 3 months and VAS score =4; 4. Aged between 18 and 65; 5. No acupuncture therapy during the past 3 months before enrollment; 6. Voluntarily participating in this trial with a written informed consent form.
Exclusion criteria
Exclusion criteria: Participants with the following conditions will be excluded: 1. Suicidal ideation or SCL-90 score >26; 2. Bipolar disorder; 3. Malignant pain caused by cancer pain syndrome; 4. Severity pain, VAS =7; 5. Headache and visceral pain such as stomachache; 6. Pregnancy or breastfeeding women; 7. Complications of severe systematic diseases such as diabetes mellitus, tumors or other considered not suitable to participate the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| depressive symptoms;severity of pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| cognitive function;quality of life;Serum BDNF protein level;mRNA of BDNF;BDNF methylation; | — |
Countries
China
Contacts
Public ContactFu Wenbin
Department of Acupuncture and Moxibusti second affiliated hospital of Guangzhou University of Chines Medicine
Outcome results
None listed