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The protective effect of erythropoietin on extracorporeal circulation lung injury and its mechanism.

The protective effect of erythropoietin on extracorporeal circulation lung injury and its mechanism.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014722
Enrollment
Unknown
Registered
2018-01-31
Start date
2018-02-22
Completion date
Unknown
Last updated
2018-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung injury after extracorporeal circulation

Interventions

Experimental group:Erythropoietin group
control group:normal saline group

Sponsors

Second Affiliated Hospital Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with cardiac surgery under extracorporeal circulation; 2. Man or woman is allowed; 3. Aged 18 to 65 years old; 4. The ASA grade II-III.

Exclusion criteria

Exclusion criteria: 1. The liver and kidney dysfunction; 2. There is an infectious disease before surgery; 3. There are acute lung injury and chronic obstructive pulmonary disease; 4. Preoperative untreated hypertension; 5. Hemoglobin reached 160g/L before surgery.

Design outcomes

Primary

MeasureTime frame
The indicator of ventilation and oxygenation;The concentration of inflammatory factors in peripheral blood;mechanical ventilation time in ICU;the duration of ICU treatment;The time from operation to discharge;days in hospital;

Countries

China

Contacts

Public ContactLIN XUE

Second Affiliated Hospital Harbin Medical University

2443837460@qq.com+86 13796674236

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026