pancreatic cancer
Conditions
Interventions
Conventional dose group:radiotherapy
High-dose group:radiotherapy
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
20 Years to 85 Years
Inclusion criteria
Inclusion criteria: Patients who met all of the following criteria were enrolled: 1. Clinical or pathological confirmed as pancreatic cancer, multi-disciplinary assessment can not surgery or refused surgery; 2. The largest tumor diameter = 7.5cm; 3. ECOG score of 0 -2 points; 4. more than 20 years old, less than 85 years old; 5. To be expected survival of more than 3 months; 6. Blood biochemical tests: bilirubin <1.5 × upper limit of normal (ULN); aspartate aminotransferase or alanine aminotransferase <5 × ULN; serum creatinine <1.0 × ULN; 7. Blood requirements: hemoglobin = 9 g/dL; platelets = 70,000/mL; neutrophils absolute value = 1500/mL; 8. patients with local recurrence of pancreatic cancer after tumor bed; 9. Quasi-radiotherapy site past no history of radiation therapy; 10. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. poor health, ECOG score = 3 points; 2. a lot of ascites, or extensive abdominal metastasis; 3. Previous abdomen received external radiotherapy or radioactive I125 particle implantation; 4. are participating in other clinical trials; 5. Gestational or lactating women; 6. There are serious neurological diseases, can not clearly tell the treatment responders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective Response Rate;Toxic and side effects; | — |
Countries
China
Contacts
Public ContactDong Lihua
The First Hospital of Jilin University
Outcome results
None listed