difficult Intubation
Conditions
Interventions
dexmedetomidine and ketamine:Intravenous injection with dexmedetomidine before intubation
midazolam and fentanyl:Intravenous injection with midazolam and fentanyl before intubation
Sponsors
Shanghai Ninth People's Hospital, School Of Medicine, Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
2 Years to 8 Years
Inclusion criteria
Inclusion criteria: (1) ASA I-II; (2) Aged from 2 to 8 years old; (3) Elective surgery for children under general anesthesia; (4) Children needs nasal fiber bronchoscopy with spontaneous breathing.
Exclusion criteria
Exclusion criteria: (1) Allergic to study drugs; (2) A history of cardiovascular disease,abnormal liver/kidney/coagulation/nervous system function; (3) Cardia arrhythmia; (4) Any congenital malformation disease; (5) difficult mask ventilation; (6) Children who refuse to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation success rate for the first time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation score and BIS value before cricothyroid membrane puncture;Intubation score and intubation time;Hemodynamic changes and the incidence of serious complications during intubation; | — |
Countries
China
Contacts
Public ContactLiu Jinxing
Shanghai Ninth People's Hospital, School Of Medicine, Shanghai Jiaotong University
Outcome results
None listed