Schizophrenia with obsessive-compulsive symptoms
Conditions
Interventions
obsessive-compulsive disorder group:no
schizophrenia with obsessive-compulsive symptoms group:no
schizophrenia with antipsychotic drug-induced obsessive-compulsive symptoms:no
Sponsors
Zhejiang Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: Obsessive-compulsive disorder group: 1. diagnosis of a OCD according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-V); 2. Aged 18-60 years; 3. Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) score more than 16 points; 4. right handed. Schizophrenia with obsessive-compulsive symptoms group: 1. diagnosis of a schizophrenia according to DSM-V, 2. obsessive-compulsive symptoms appear before the antipsychotics treatment, 3. YBOCS score more than 16 points. 4. Aged 18-60 years; 5. Right handed. Schizophrenia with clozapine-induced obsessive-compulsive symptoms group: 1. diagnosis of a schizophrenia-spectrum disorder according to DSM-V; 2. no obsessive-compulsive symptoms before treatment with clozapine; 3. monotherapy with clozapine; 4. stable medication and psychopathology over a period of at least 2 weeks; 5. Aged 18-60 years; 6. Y-BOCS score more than 16 points; 7. right handed.
Exclusion criteria
Exclusion criteria: 1. secondary obsessive-compulsive symptoms of cerebral organic disease, especially basal ganglia disease; 2. obsessive-compulsive symptoms with severe heart, liver or renal insufficiency; 3. have accepted no convulsive electroconvulsive therapy in the last 6 months; 4. Alcohol or drug addicts; 5. women in pregnancy; 6. left handed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neroimaging; | — |
Countries
China
Contacts
Public ContactLIU LAN YING
Zhejiang Academy of Traditional Chinese Medicine
Outcome results
None listed