patients underwent major spine surgery
Conditions
Interventions
1:control group
Sponsors
Department of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA I to II; 2. Age from 40-70 years; 3. Patients undergoing elective posterior nucleus pulposus of lumbar spinal nerve resection lysis of vertebral with fixed cage implantation surgery for their spinal stenosis and degenerating intervertebral disc, which are diagnosed with radiographic evidence(no disruption of annulus fibrosus of intervertebral disc).
Exclusion criteria
Exclusion criteria: 1. History of previous immune system diseases; 2. No infection in last week before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anesthetic dosage, output volume, urine volume, operative time, anesthetic time, acupoint intensity and frequency, stopping time, postoperative recovery time, extubation time, etc.; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM Constitution, body temperature, VAS pain score, nausea and vomiting, abdominal distension, the first time of exhaust, dizziness, respiratory depression, thigh numbness, skin itching and comfort.;IgG, IgM, CD19+CD3-B cell;Cellular immunity: the activity of NK cells, T cells, CD3 + CD4 + CD8 + T cells, T cells, CD56 + T cells, cytokines: IL-2 and IL-10 (flow cytometry was used to detect the activity of NK cells and CD19+CD3-B cells, CD3+T cells, CD4+T cells, CD8+T cells and IL-10 IL-2 percentage; | — |
Countries
China
Contacts
Public ContactLi Yuhui
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed