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The effect and mechanism of Transcutaneous electric nerve stimulation (TN) Therapy on Primary Biliary Cholangitis (PBC)

The effect and mechanism of Transcutaneous electric nerve stimulation (TN) Therapy on Primary Biliary Cholangitis (PBC)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014633
Enrollment
Unknown
Registered
2018-01-25
Start date
2018-01-25
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Biliary Cholangitis, PBC

Interventions

Case group:Transcutaneous electric nerve stimulation
control group:No

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Based on EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis.

Exclusion criteria

Exclusion criteria: 1. Cases with pruritus; 2. Imaging: F4 from vibration-controlled transient elastography (VCTE) or cirrhosis; 3. Cases combined with other liver diseases or other immune-related diseases; 4. Cases in acute stage; 5. Cases in disagreement with the research; 6. Normal level of liver function.

Design outcomes

Primary

MeasureTime frame
bile acids;AST;ALT;?-GT;ALP;TC;TG;Index of Fibrosis;TNF-a;IL-1;IL-6;IL-10;fecal microbiomes;HRV;endotoxin;D-lactic acid;diamine oxidase;7a-hydroxy-4-cholesten-3-one;Fibroblast Growth Factor 19 (FGF-19);relative metabolites of gut microbiota;—

Countries

China

Contacts

Public ContactZhijun Duan, Lixia Wang, Zhifeng Zhang, Dong Yang

The First Affiliated Hospital of Dalian Medical University

cathydoctor@sina.com+86 18098875588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026