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Improvement of vascular endothelial dysfunction induced by exercise and diet control associated with serum microRNA-126 in obese adolescents

The exercise intervention and mechanism of vascular endothelial dysfunction in simple obesity children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014631
Enrollment
Unknown
Registered
2018-01-25
Start date
2016-04-15
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity and vascular endothelial dysfunction

Interventions

Experiment Group:exercise intervention
Experiment Group:Diet Intervention
Control Group:normal life behavior

Sponsors

Beijing Normal University Physical Education and Sports Department
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: In this study, 32 male obese adolescents with obesity diet were selected as experimental subjects (EC). Inclusion criteria obesity standards in accordance with the "Chinese school-age children and adolescents overweight, obesity screening body mass index value classification criteria" to determine. Other inclusion criteria include no cardiovascular disease, kidney disease, no history of smoking, nearly 6 months without taking any hormonal drugs, usually no regular exercise habits. At the same time, 10 normal healthy male adolescents were selected as control group (CG).

Exclusion criteria

Exclusion criteria: Cardiovascular disease, kidney disease, smoking history, nearly 6 months of taking any hormone drugs, usually have regular exercise habits.

Design outcomes

Primary

MeasureTime frame
eNOS;ET-1;microRNA-126;RHI;

Countries

China

Contacts

Public ContactTang Donghui

Beijing Normal University Department of Physical Education and Sport

tdh1964@163.com+86 15210951721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026