the regulation of calcium-phosphate metabolism disorders in patients with ESRD
Conditions
Interventions
Sponsors
Subei People's Hospital, Yangzhou
Eligibility
Sex/Gender
All
Age
26 Years to 73 Years
Inclusion criteria
Inclusion criteria: patients diagnosed with stage 5 chronic kidney disease (CKD; eGFR<15ml/min/1.73m2), with eGFR calculated using the creatinine-based Modification of Diet in Renal Disease Study equation
Exclusion criteria
Exclusion criteria: 1) Patients having received a kidney transplant; 2) Patients who were taking medication that affected the levels of Ca or Pi, such as a Ca-Pi binder or calcitriol; 3) Patients who had received parathyroid surgery or who had primary hyperparathyrodism; 4) Patients with severe infection, cardiovascular disease, or cerebrovascular disease; 5) Patients with wasting disease, such as connective tissue disease, hepatobiliary disease, or a malignant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum calcium;serum phosphate;Klotho protein;FGF23;iPTH; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobin;albumin; | — |
Countries
China
Contacts
Public ContactChanghua Liu
Subei People's Hospital, Yangzhou
Outcome results
None listed