Asherman's syndrome and thinned endometrium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 20-40 years-old; 2. Previous hysteroscopy diagnosis of intrauterine adhesions, thinned endometrium or endometrial atrophy; 3. previously endometrium thickness =5mm during pre-ovulatory phase of natural cycle or hormone replacement therapy (HRT)cycle; 4. Normal liver, heart and kidney function; 5. Absence of psychiatric pathology and ability to accomplish the treatment; 6. ß-hCG negative; 7. Absence of STDs, hepatitis B or hepatitis C; 8. At least 2 high quality D3 embryos available for ET; 9. willingness to join and complete this study.
Exclusion criteria
Exclusion criteria: 1. Acute urogenital infection; 2. Combined with other genital disease ingcluding hysteromyoma, adenomyosis, hydrosalpinx or other chronic disease that incapable for pregnancy; 3. Allergy to G-CSF or contraindication to G-CSF.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness;Endometrial blood flow;Biochemical pregnancy rate;Clinical pregnancy rate;Continue the pregnancy rate;Miscarriage rate;Endometrial shape; | — |
Countries
China
Contacts
the First Affiliated Hospital of Guangxi Medical University