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Autologous bone marrow derived stem cells in the treatment of intrauterine adhesions and thin endometrium

Autologous bone marrow derived stem cells in the treatment of intrauterine adhesions and thin endometrium

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014601
Enrollment
Unknown
Registered
2018-01-23
Start date
2018-02-01
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asherman's syndrome and thinned endometrium

Interventions

BSC:BSC perfusion
G-GSF group:G-GSFperfusion

Sponsors

the First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Age 20-40 years-old; 2. Previous hysteroscopy diagnosis of intrauterine adhesions, thinned endometrium or endometrial atrophy; 3. previously endometrium thickness =5mm during pre-ovulatory phase of natural cycle or hormone replacement therapy (HRT)cycle; 4. Normal liver, heart and kidney function; 5. Absence of psychiatric pathology and ability to accomplish the treatment; 6. ß-hCG negative; 7. Absence of STDs, hepatitis B or hepatitis C; 8. At least 2 high quality D3 embryos available for ET; 9. willingness to join and complete this study.

Exclusion criteria

Exclusion criteria: 1. Acute urogenital infection; 2. Combined with other genital disease ingcluding hysteromyoma, adenomyosis, hydrosalpinx or other chronic disease that incapable for pregnancy; 3. Allergy to G-CSF or contraindication to G-CSF.

Design outcomes

Primary

MeasureTime frame
Endometrial thickness;Endometrial blood flow;Biochemical pregnancy rate;Clinical pregnancy rate;Continue the pregnancy rate;Miscarriage rate;Endometrial shape;

Countries

China

Contacts

Public ContactQin Aiping

the First Affiliated Hospital of Guangxi Medical University

aini02456@126.com+86 13977102456

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026