Major depressive disorder
Conditions
Sponsors
Mental Health Institute, The second xiangya hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Patients meeting DSM-IV diagnostic criteria of major depressive disorder; 2. HAMD scores not less than 20 points; 3. Age from 18-45 years; 4. Education years >= 12 years; 5. The Han nationality, right handness; 6. Informed consent.
Exclusion criteria
Exclusion criteria: 1. With psychotic symptoms; 2. With a history of alcohol and drug dependence; 3. With organic disease of brain and severe somatic disease; 4. With history of coma after brain trauma; 5. Woman with pregnancy or lactation period; 6. With a history of seizures or with a family history of epilepsy; 7. Received drugs in 6 hours before MRI scan; 8. Exclusion of other diseases; 9. With contraindications of MRI scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain structure;Brain function;Cortisol;gene; | — |
Countries
China
Contacts
Public ContactLI Lingjiang
Mental Health Institute, The second xiangya hospital, Central South University
Outcome results
None listed