irritable bowel syndrome
Conditions
Interventions
Acupuncture group (therapy group):the auricular branch of the vagal nerve (auricular t-VNS)
Control:Fake acupuncture
Sponsors
Guangdong Provincial Hospital of TCM; the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. meet the diagnostic criteria of Rome III IBS, colonoscopy to exclude other diseases caused by constipation, abdominal pain; 2. men and women, aged 18 to 65 years; 3. nearly two months to take IBS medication; 4. in vivo No metal implants, no claustrophobia and other MRI and other MRI contraindications; 5. with reading and writing ability and can cooperate with the examination and treatment; 6. subjects informed, voluntarily received tVNS treatment and signed informed consent. (Note: At the same time meet the above criteria included parties).
Exclusion criteria
Exclusion criteria: 1. Those who did not meet the above diagnostic criteria; 2. Anxiety scale greater than or equal to 50, as measured by Self-rating Anxiety Scale (SAS) or Self-rating Depression Scale (SDS) Or depression patients; 3. with cardiovascular and cerebrovascular, liver, kidney and hematopoietic system and other serious life-threatening primary diseases and mental patients; 4. pregnant or pregnant women, lactating women; 5. can not adhere to tVNS treatment and can not understand the amount of Table person. (Note: those who meet one or more of those who exclude).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of days of IBS attack /30 days;IBS specific quality of life questionnaire(IBS-QOL);Symptoms points;Regional Homogeneity (ReHo);Brain Functional Connectivity Analysis;Fanctional Network Analysis; | — |
Countries
China
Contacts
Public ContactChen Jun
Guangdong Provincial Hospital of TCM; the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Outcome results
None listed