Critical Care Patients in ICU
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) ICU critically ill patients who need for early enteral nutrition support(APACH II score more than 8 points); (2) age > 18 years; (3) expected to stay in ICU more than 5 day.
Exclusion criteria
Exclusion criteria: (1) pregnant women; (2) patients with organ transplantation, advanced malignant tumor and brain death; (3) enteral or parenteral nutrition support has begun to be accepted before ICU; (4) patients with intestinal obstruction, intestinal fistula, gastrointestinal tract ischemia and active gastrointestinal bleeding were not suitable for enteral nutrition. (5) patients who are expected to die within 72h; (6) patients who refused to participate in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| procalcitonin;Routine blood test;C reactive protein;Sputum culture;blood culture;Urine culture;Chest radiograph;Live time of ICU;Reach the target feeding time;Mechanical ventilation time;Mortality rate;New infection rates (based on CDC diagnostic criteria); | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;renal function;Electrolyte;Arterial blood gas analysis;Diffused intravascular coagulation;Complete set of myocardial infarction;Fungus G polydextrose;cellular immunity;Interleukin-6;The incidence of reflux error;GRV; | — |
Countries
China
Contacts
Shanghai Sixth People's Hospital