Parkinson's Disease
Conditions
Interventions
PD group:propofol
NPD group:propofol
Sponsors
Xuanwu Hospital of CCMU
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. ASA grades I-II; 2. Age 18 - 65 years; 3. BMI< 35; 4. No severe respiratory and circulatory diseases; 5. Patients signed informed consent, and approved by the hospital ethics Committee, etc. Pd: diagnosis of Parkinson's disease during hospitalization, selective DBS treatment, in line with surgical indications (excluding dementia, etc.);
Exclusion criteria
Exclusion criteria: 1. Patients allergic to propofol; 2. Lipids metabolism disorder; 3. Alcoholics; 4. Patients with bis of less than 80 when entering operating room; 5. After induction, the mean arterial pressure decreased by more than 20 % 6. Patients with severe respiratory and circulatory diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BIS value; | — |
Secondary
| Measure | Time frame |
|---|---|
| age;gender;Body Mass Index;state of consciousness before operation;Blood pressure;MAP;HR;SpO2;PET CO2;temperature;ASA status;NYHA functional class;MET class;complication of other systems;length of surgery;infusion volume;lost volume;whether extubation;postoperative consciousness;postoperative whereabouts;hospital stay; | — |
Countries
China
Contacts
Public ContactZHAO LEI
Xuanwu Hospital of CCMU
Outcome results
None listed