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Screening of biomarkers of phlegm-dampness syndrome based on microRNA expression in patients with polycystic ovary syndrome and study on its intervention

Screening of biomarkers of phlegm-dampness syndrome based on microRNA expression in patients with polycystic ovary syndrome and study on its intervention

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014518
Enrollment
Unknown
Registered
2018-01-18
Start date
2018-01-20
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Interventions

first:PCOS phlegm type
second:pcos non-phlegm type
third:pcos phlegm treatment
fourth:Non-PCOS non-phlegm
fifth:Non-PCOS phlegm

Sponsors

Shandong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 41 Years

Inclusion criteria

Inclusion criteria: PCOS diagnostic criteria: PCOS diagnostic criteria were co-sponsored in Rotterdam in 2003 by the European Society for Human Reproduction (ESHRE) and the American Society of Reproductive Medicine (ASRM). Diagnostic criteria for phlegm-dampness syndrome: According to "Criteria for TCM Syndrome Differentiation and Treatment", "Diagnostic Criteria for Internal and External Diseases of Chinese, Women and Children", "General Practices of TCM Diagnosis and Treatment" and "Gynecology of Traditional Chinese Medicine". Traditional Chinese medicine to develop phlegm syndrome criteria are as follows: cycle delay, by the amount of less, by the color of red, qualitative sticky sputum, or gradually amenorrhea, or marriage for a long time infertility; thoracic and abdominal fullness: Easy nausea and vomiting; Pale tongue or toothed, greasy moss; pulse slip "The above symptoms must have, and see the rest of the three, you can diagnose" Criteria for determination of phlegm-dampness: Refer to "Classification and Determination of Traditional Chinese Medicine Constitution" (Chinese Society of Traditional Chinese Medicine 2009.4) Choose normal-aged women of phlegm-dampness constitution. Phlegm-dampness characteristics: body fat, full and soft belly. Easy to sweat, and more sticky. Often feel a layer of oil on face. Regulation: diet should be light, you can eat more melon and so on. Due to body fat, easy to sleepy, it should be based on their specific circumstances step by step, long-term adhere to exercise.

Exclusion criteria

Exclusion criteria: Adrenal, thyroid, pituitary and other endocrine dysfunction patients, such as adrenal hyperplasia, adrenal insufficiency, hyperthyroidism, hypothyroidism, pituitary tumors, Shear's syndrome, diabetes; cardiovascular and cerebrovascular diseases such as hypertension, Coronary heart disease, etc.; liver and kidney disease patients; neurological, mental illness patients; blood disease; acute genitourinary system inflammation patients; reproductive system cancer patients; genital organic disease; contraceptives within three months or other hormones Patients with drugs; Physiological menopause and amenorrhea; Patients with poor compliance

Design outcomes

Primary

MeasureTime frame
Granulosa cells;Follicular fluid;

Countries

China

Contacts

Public ContactNing Zhang

Shandong Provincial Hospital of Traditional Chinese Medicine

ning_zhang1975@163.com+86 18766101739

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026