prostate cancer
Conditions
Interventions
Gold Standard:For patients who received the operation, operative pathology was used as the gold standard
for patients who did not receive the operation, the final diagnosis of one year follow-up was used as the gold standard.
Index test:MRI-TRUS 
combined 
with 
systematic 
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Aged = 18 years old; (2) Serum PSA was = 4ng/ml due to unexplained reasons; (3) Suspected nodules were detected by initial rectal ultrasound or MRI examination; (4) Patients that had not received puncture biopsy; (5) Patients were able to understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Acute prostatitis; (2) Coagulation dysfunction; (3) Low immune function; (4) Anal fistula or colorectal condition that did not allow puncture biopsy; (5) There were other serious diseases that were not suitable for puncture biopsy; (6) the mental state was not suitable; (7) Patients with pacemaker or automatic implantable defibrillator; (8) Patients with allergies to any known adhesives or latex.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of high-risk patients (for all punctured tissues, Gleason score =4+3 was high risk; for postoperative pathological examination, tissues with Gleason score =4+3 were high risk); | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of moderate risk patients (for targeted puncture tissues, =50% tissues with Gleason score=4+3; for systematic puncture tissues, =33% tissues with Gleason score=4+3; for postoperative pathological examination, =20% tissues with Gleason score=4+3).;Percentage of low risk patients (for targeted puncture tissues, <50% tissues with Gleason score=4+3 or Gleason score<7; for systematic puncture tissues, <33% tissues with Gleason score=4+3 or Gleason score<7; for postoperative pathological examination, <20% tissues with Gleason score=4+3 or Gleason score<7).;Preoperative anxiety (Amsterdam preoperative anxiety and information scale, APAIS);Pain score (VRS score);Disease progress: tumor size, lesion number, recurrence or not, recurrence time, metastasis or not, metastasis time, and etc.; | — |
Countries
China
Contacts
Public ContactLigang Cui
Peking University Third Hospital
Outcome results
None listed