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The relationship between blood pressure and recanalization in acute ischemic stroke with intravenous thrombolysis therapy: a real-time TCD monitoring study

The relationship between blood pressure and recanalization in acute ischemic stroke with intravenous thrombolysis therapy: a real-time TCD monitoring study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014495
Enrollment
Unknown
Registered
2018-01-17
Start date
2018-02-01
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute ischemic stroke

Interventions

Case series:receive intravenous thrombolysis

Sponsors

Beijing Tshinghua Changgung Hospital of Tsinghua University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Acute ischaemic stroke patients who receive intravenous thrombolysis; 2. Informed patient consent or personal consultee declaration form; 3. Male or female, aged 18 years or above; 4. Able (in the Investigator's opinion) and willing to comply with all study requirements; 5. Willing to allow his or her General Practitioner (GP) to be notified of participation in the study.

Exclusion criteria

Exclusion criteria: 1. Unable (in the Investigator's opinion) or unwilling to comply with any study requirements; 2. Significant pre-stroke dependency (premorbid Modified Rankin Score >3); 3. Co-morbidity with anticipated life expectancy less than 3 months; 4. Current participation in another investigational drug trial.

Design outcomes

Primary

MeasureTime frame
The relationship between the decline of systolic blood pressure (?SBP=20mmHg or ?DBP=10mmHg) and recanalization (measured as the odds ratio of those two dichotomous variables);The relationship between the decline of blood pressure (?SBP=20mmHg or ?DBP=10mmHg) and clinical neurological improvement (NIHSS=1 or 0 and ?NIHSS=4 at 24h) (measured as the odds ratio of those two dichotomous variables);

Countries

China

Contacts

Public ContactWu jian
wujianxuanwu@126.com+86 13466766485

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026