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Effects on postoperative delirium and cognitive function of acute hypervolemic fluid infusion during induction of general anesthesia in elderly patients undergoing gastrointestinal operations

Effects on postoperative delirium and cognitive function of acute hypervolemic fluid infusion during induction of general anesthesia in elderly patients undergoing gastrointestinal operations

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014474
Enrollment
Unknown
Registered
2018-01-16
Start date
2017-10-01
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tumor in gastrointestinal

Interventions

H Group:acute hypervolemic fluid infusion during induction of general anesthesia

Sponsors

Ruijin Hospital Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: Age 60-85 years; ASA I-III; BMI 18-35kg/m2; Patients undergoing endoscopic gastrointestinal cancer surgery

Exclusion criteria

Exclusion criteria: History of severe heart, lung, liver, kidney and brain diseases; Preoperative Hct <27% or HB <80g/L; Mental disorder and consciousness disorder existed before operation; Take psychoactive drugs before operation; Preoperative delirium; Preoperative MMSE score < 23

Design outcomes

Primary

MeasureTime frame
postoperative delirium;Postoperative Cognitive Dysfunction;Dosage and times of vasoactive drugs during operation;PH, Lac, BE value of Arterial blood gas analysis at the end of the operation;

Secondary

MeasureTime frame
Hemodynamic indicators;VAS;nausea and vomiting score;postoperative complications;first exhaust time;postoperative hospitalization time;

Countries

China

Contacts

Public ContactLuo Yan

Ruijin Hospital Shanghai Jiao Tong University School of Medicine

13916323078@163.com+86 13916323078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026