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Endometrial injury increases Hypoxia-inducible factor expression and angiogenesis in the endometrium of women with recurrent implantation failure

Endometrial injury increases Hypoxia-inducible factor expression and angiogenesis in the endometrium of women with recurrent implantation failure

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014472
Enrollment
Unknown
Registered
2018-01-16
Start date
2018-01-20
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RIF

Interventions

Intervention Group:Endometrial injury
Control Group:none

Sponsors

Infertility Center, Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Endometrial tissues were obtained from twenty women undergoing in vitro fertilization (IVF) who had at least three previous failed treatment cycles; normal endometrial specimens were obtained from ten fertile control women.

Exclusion criteria

Exclusion criteria: None of the patients had received steroid hormone therapy (HT) within the previous 3 months, and none exhibited any obvious internal medicine or surgical comorbidities. Women with endometrial abnormalities, hydrosalpinx, endometriosis, fibroids, ovarian cysts, or lesions were excluded.

Design outcomes

Primary

MeasureTime frame
endometriosis;HIF;—

Countries

China

Contacts

Public ContactXiaohui Deng, PhD

Infertility Center, Qilu Hospital of Shandong University

dxh_sdqlsz@163.com+86 18660779878

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026