Allergic rhinitis
Conditions
Interventions
Treatment group:Yiqigubiao granule + Loratadine Tablets
control group:Yiqi Gubiao granule placebo + Loratadine Tablets
Sponsors
Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet The diagnostic criteria of allergic rhinitis acute phase; 2. aged 18~65 years; 3. The total course of disease was more than one year, and the acute attack was less than 72 hours; 4. The subjects signed informed consent.
Exclusion criteria
Exclusion criteria: (1) patients with upper respiratory tract infection, eosinophilia, vasomotor rhinitis, and nasal polyps have similar symptoms of allergic rhinitis; (2) the drug who has been used in the treatment of allergic rhinitis within one week of this disease; (3) patients with pneumonia, bronchitis and asthma; (4) women in pregnancy and lactation; (5) patients with severe primary heart, liver, lung, kidney, blood diseases and diabetes or serious diseases that affect their survival; (6) The mental or behavioral disorders because they cannot give full informed consent; (7) The suspected alcohol and drug abuse history; (8) According to the researcher's judgment, can reduce the possibility of the group or other lesions into the group is complicated, such as work environment change often causes lost condition; (9) To allergies, as of two or more drugs or food allergy, or known allergy to the drug ingredients; (10) The other is to participate in the clinical trial subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sneeze;Runny nose;nasal obstruction;Nasal itching;Routine blood test;Urine routine test;electrocardiogram;liver function test;Renal function test;IL-6;TNF;total IgE;adverse events;Clinical signs: the color of the nasal mucosa, the degree of edema, the change of nasal turbinate.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sweating, chill, itching, itching; | — |
Countries
China
Contacts
Public ContactZhang Zhongde
Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed