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Effect of intravenous lidocaine on postoperative pain and the quality of recovery in adults undergoing total knee arthroplasty

Effect of intravenous lidocaine on postoperative pain and the quality of recovery in adults undergoing total knee arthroplasty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014410
Enrollment
Unknown
Registered
2018-01-12
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total knee arthroplasty

Interventions

Lidocaine group:i.v.-bolus injection of 1.5mg/kg at induction of anaesthesia, followed by an infusion of 1.5mg/kg/h until the end of surgery
Control group:Infusion of saline of the same volume

Sponsors

Dept. of Anesthesiology,The Affliliated Hospital Of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients undergoing total knee arthroplasty, aged more than 18 to 75 years old, ASA I~? level, signed informed consent.

Exclusion criteria

Exclusion criteria: patients with a history of cardiac, renal or hepatic disease, psychological disorders, allergy to study medications, and any other contraindication for general anesthesia.

Design outcomes

Primary

MeasureTime frame
postoperative pain scoresl;—

Secondary

MeasureTime frame
Scores on QoR-15;plasma levels of Inflammatory markers;postoperative opioid or non-steroidal anti-inflammatory drugs requirements;the incidence of pruritus, postoperative nausea and vomiting;—

Countries

China

Contacts

Public ContactLiu Jindong

Affiliated Hospital of Xuzhou Medical University

Liujindong1818@163.com+86 13951355136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026