sepsis induced acute kidney injury
Conditions
Interventions
Gold Standard:AKI diagnostic criteria: Scr rose within 48h = 0.3 mg/dL (= 26.5µmol / L),or SCr> 1.5 times baseline value within 7 days Or 6 h urine output <0.5ml/(kg.h)
The baseline Scr value is defined as the lowest known 3-month Scr,such as,Scr unknown before admission is the lowest value afte
Index test:insulin-like 
factor-binding 
protein-7,IGFBP-7
Sponsors
Tianjin First Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years; 2. Patients with sepsis without underlying kidney disease; 3. No AKI occurred when entering the ICU.
Exclusion criteria
Exclusion criteria: 1. With chronic kidney disease; 2. Urinary tract infections have occurred on admission; 3. AKI has occurred on admission; 4. Have been exposed to nephrotoxic drugs before enter the ICU for at least one week; 5. Excluding other reasons cause AKI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IGFBP-7;NGAL;sCr;sCys-C;Urine volume; | — |
Countries
China
Contacts
Public ContactYang Shuying
Tianjin First Center Hospital
Outcome results
None listed