Knee osteoarthritis
Conditions
Interventions
treatment group: evidence-based traditional Chinese medicine massage treatment
control group:external using Diclofenac Diethylamine Emulgel
Sponsors
Guang'anmen Hospital, China Acadamy of Chinese Medicine Science
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. According with the diagnostic criteria of knee osteoarthritis; 2. Grade 1~3 of K-L grades; 3. The WOMAC score = 25 points; 4. 40~80 years old; 5. The informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary osteoarthritis; 2. Osteoarthritis of the knee with joint effusion more than medium degree or meniscus injury more than third degree; 3. Patients received intra-articular injection of sodium hyaluronate or hormone within 3 months. 4. Patients with severe osteoporosis, diabetes, lower extremity vascular disease, limb deformity and nervous system disease; 5. Patients with serious mental disorders, can not understand or express feeling correctly. 6. The women who is pregnant, preparing for pregnancy, or lactating women; 7. Patient with serious disease with heart, lung, brain, liver, kidney and hematopoietic system; 8. Patient with contraindications of MRI; 9. Patient who is allergy to test drugs, allergic constitution patient; 10. Patient who is participating in other clinical trial; 11. Patient who indulge in excessive drinking and / or psychoactive substances, drug abusers and addicts; According to the researchers judgment, patient has the disease or other conditions that can reduce or complicate the possibility to be recruited, such as unstable working or living environment, that will cause the loss of follow-up.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| the Patient-Reported knee osteoarthritis TCM syndrome evaluation scale;space of joint on x-ray photo;cartilage morphology on MRI;The dosage of NSAIDs; | — |
Primary
| Measure | Time frame |
|---|---|
| WOMAC; | — |
Countries
China
Contacts
Public ContactLi-Min Xie
Guang'anmen Hospital, China Acadamy of Chinese Medicine Science
Outcome results
None listed