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The effects of multidimensional psychological interventions on the chemotherapy response in patients with epithelial ovarian cancer: a prospective multi-center trial

The effects of multidimensional psychological interventions on the chemotherapy response in patients with epithelial ovarian cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014398
Enrollment
Unknown
Registered
2018-01-10
Start date
2018-04-01
Completion date
Unknown
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ovarian cancer

Interventions

experimental group:cognitive health education
experimental group:behavioral interventions

Sponsors

Obstetrics&Gynecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with pelvic masses that are confirmed by paraffin-embedded sections to be primary or recurrent epithelial ovarian/peritoneal/fallopian tube cancer; 2. The lesions are sufficiently big so that the obtaining of the specimens won't affect the pathologic diagnosis; 3. Life expectancy of at least 12 months.

Exclusion criteria

Exclusion criteria: 1. Diagnosed with primary cancer of another organ; 2. The paraffin-embedded sections confirmed the pelvic masses to be non-epithelial cancer; 3. Having received treatments involving systemic corticosteroids within 4 months; 4. The participation of other clinical trials within 4 weeks; 5. Aged < 18 years; 6. Suffering from other diseases including respiratory diseases/biliary diseases/cardiac diseases (CHF class II or higher)/high blood pressure/hematological diseases/abnormal liver and kidney function(with any index one time higher than the superior limit)/ brain diseases with impaired judgment and so on; 7. Abuse of drug or alcohol 8. Suffering from other diseases that can influence the immune response of the body; 9. During pregnancy or lactation; 10. Requesting of concealment of the history of the disease.

Design outcomes

Primary

MeasureTime frame
the results of PHQ-9;the results of GAD-7;chemotherapy response;noradrenaline level in serum;cortisol level in serum;IL-6 level in serum;noradrenaline level in tumor tissues;

Secondary

MeasureTime frame
the results of FACT-O;

Countries

China

Contacts

Public ContactKang Yu

Obstetrics & Gynecology Hospital of Fudan University

yukang@fudan.edu.cn+86 13636328211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026