Squamous cell carcinoma of oral cavity
Conditions
Interventions
Group:Chemotherapy combined with ultrasonic heating
Control group:Chemotherapy
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age over 18 years old (including 18 years old), under 75 years old (including 75 years old), male and female; (2) diagnosis of oral squamous cell carcinoma by histopathology; (3) ECOG score 0 to 2 points, is expected to live longer than 6 months; (4) clinical staging in line with local advanced (III ~ IV, refer to the seventh edition UICC / AJCC staging system [22]), including unresectable tumors; (5) before the trial signed informed consent, voluntarily participate in the test; (6) good compliance; (7) blood, blood sugar and liver, kidney, lung function and other normal; (8) female pregnancy test subjects pregnancy test negative, must agree to use effective contraceptive measures to ensure that during the trial and stop treatment within 3 months after pregnancy is not pregnant.
Exclusion criteria
Exclusion criteria: (1) failure to obtain signed informed consent; (2) pregnant, lactating women; (3) vital organs dysfunction, the existence of life-threatening; (4) patients who have received radiotherapy locally; (5) local skin ulceration, open wound; (6) clear distant metastases or other malignancies; (7) known to have allergic reactions to chemotherapy drugs; (8) suffering from mental illness, can not cooperate with the treatment; (9) have febrile disease, can not control the symptoms; (10) abnormal coagulation, bleeding tendency; (11) had participated in other clinical trials in the past 30 days; (12) other investigators believe that inappropriate treatment of the situation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Target lesion diameter; | — |
Countries
China
Contacts
Public ContactGuo Wei
Shanghai Jiaotong University School of Medicine Affiliated Ninth People's Hospital
Outcome results
None listed