coffee intervention
Conditions
Interventions
2 Cohorts:coffee versus no coffee
Sponsors
the Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Between the ages of 18 and 65, inclusive of 18 and 65 years old; 2. Normal and high-risk groups of diabetes; 3. For women of childbearing age, urine pregnancy test is negative; 4. Patient signs informed consent; 5. No diabetes, heart disease, liver and kidney disease, gastrointestinal diseases, endocrine diseases, sleep disorders.
Exclusion criteria
Exclusion criteria: 1. Female patients who are pregnant, breastfeeding or planning pregnancy during the trial; 2. people who has severe arrhythmia and other cardiovascular adverse events after drinking coffee; 3. Patients with overt liver or kidney disease (ALT or AST 2-3 times upper limit of normal, or T-Bil 1.5 times upper limit of normal, or Cr> 115 µmol/L); 4. Serum triglycerides> 5mmol/L; 5. people who have severe arrhythmia, unstable or severe angina, cardiac insufficiency (NYHA classification III, IV); 6. people who have malignant tumors, tuberculosis and other chronic wasting disease, blood diseases, mental illness, autoimmune diseases, significant digestion and absorption disorders, or suffered from acute cerebrovascular disease in the nearly 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood glucose;Heart rate;sleeping time; | — |
Countries
China
Contacts
Public ContactCongrong Wang
The Sixth People's Hospital Affiliated to Shanghai Jiaotong University
Outcome results
None listed