Metformin Improves the fecundity of PCOS Infertile Patients with Insulin Resistance in IVF-ET: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800014348

Enrollment

Unknown

Registered

2018-01-07

Start date

2018-03-01

Completion date

Unknown

Last updated

2018-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovarian syndrome

Interventions

1:Metformin

2:Observation

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients are diagnosed with PCOS by the 2003 Rotterdam criteria, who have insulin resistance (HOMA index > 2.77). They are infertile because of PCOS and taking IVF to get pregnancy

Exclusion criteria

Exclusion criteria: Patients who has severe systemic disease or other endocrine diseases such as diabetes, thyroid disease, adrenal disease. Patients whose embryos quality are low.

Design outcomes

Primary

Measure	Time frame
ovulation rate;live birth rate;pregnancy rate;abortion rate;	—

Countries

China

Contacts

Public ContactXiao Li

West China Second University Hospital, Sichuan University

xiaoli2006929@126.com+86 13880798247

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026