Metformin Improves the fecundity of PCOS Infertile Patients with Insulin Resistance: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800014347

Enrollment

Unknown

Registered

2018-01-07

Start date

2018-02-01

Completion date

Unknown

Last updated

2018-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovarian syndrome

Interventions

1:metformin

2:Observation

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patients are diagnosed with PCOS by the 2003 Rotterdam criteria, who have insulin resistance (HOMA index > 2.77). They are infertile because of PCOS (at least with a side of unobstructed fallopion tube.

Exclusion criteria

Exclusion criteria: Patients who has severe systemic disease or other endocrine diseases such as diabetes, thyroid disease, adrenal disease. oligospermia or azoospermia.

Design outcomes

Primary

Measure	Time frame
ovulatory rate;live birth rate;pregnancy rate;	—

Countries

China

Contacts

Public ContactHuang Wei

weihuang64@163.com+86 13881858999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026