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The concept of managing the spleen to cure the liver and treatment with a combination of traditional Chinese and Western medicine in patients with acute-on-chronic pre-liver failure

The concept of managing the spleen to cure the liver and treatment with a combination of traditional Chinese and Western medicine in patients with HBV-related acute-on-chronic pre-liver failure: A prospective randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014326
Enrollment
Unknown
Registered
2018-01-06
Start date
2018-01-05
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HBV-related acute-on-chronic pre-liver failure

Interventions

control group:Internal medicine treatment and lactulose
test group:Internal medicine treatment and method of managing the spleen to cure the liver

Sponsors

Tianjin Second People's Hospital & Tianjin Institute of Hepatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. informed consent before treatment and 2. conformation to the diagnostic criteria of pre-liver failure proposed by the Liver Failure and Artificial Liver Study Group of the Chinese Medical Association (2012 edition); 3. aged between 16 and 65 years; 4. Patients with chronic hepatitis B or compensatory iver cirrhosis of hepatitis B.

Exclusion criteria

Exclusion criteria: (1) Obstructive jaundice caused by liver tumor and bile duct stones; (2) Drug-induced hepatitis,alcoholic hepatitis and autoimmune hepatitis; (3) No other serious systemic disease such as hyperthyroidism,blood disease and so on; (4) Hepatitis B causes liver failure; (5) Other viral infections that cause liver failure; (6) Unwilling to cooperate and poor compliance.

Design outcomes

Primary

MeasureTime frame
Incidence of liver failure;Alanine transaminase;Glutamic-oxalacetic transaminease;Alkaline phosphatase;Gamma-glutamyl transpeptidase;Cholinesterase;Total bilirubin;Direct bilirubin;Albumin;Prothrombin time;Triglyceride;Total cholesterol;Blood glucose;symptoms of TCM;—

Countries

China

Contacts

Public ContactJinyan Lei

Tianjin Second People's Hospital & Tianjin Institute of Hepatology

leijinayan001@126.com+86 13612052269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026