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Efficiency of Dexmedetomidine administration for relieving anxiety to prevent new-onset postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft

Efficiency of Dexmedetomidine administration for relieving anxiety to prevent new-onset postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014314
Enrollment
Unknown
Registered
2018-01-05
Start date
2017-01-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

new-onset of postoperative atrial fibrillation

Interventions

dexmedetomidine group:infusion at a rate of 0.2-1.0ug/kg/h
propofol group:infusion at a rate of 0.1-3.0mg/kg/h

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. aged>18 years; 2. undergoing elective OPCABG; 3. willingness to provide informed consent.

Exclusion criteria

Exclusion criteria: 1. active myocardial ischemia; 2. cardiac valvular dysfunction; 3. arrhythmias (permanent or paroxysmal AF, supraventricular tachycardia, ventricular arrhythmia, second- or third-degree heart block, permanent pacemaker, and/or defibrillator); 4. history of psychiatric disorders (schizophrenia, mania, psychosis); 5. allergic to DEX or PROP (Propofol).

Design outcomes

Primary

MeasureTime frame
anxiety scale;new-onset of postoperative atrial fibrillation;—

Secondary

MeasureTime frame
new-onset of postoperative atrial fibrillation;cardiac color ultrasound;multi-organ complication;—

Countries

China

Contacts

Public ContactTan Qi

Shandong Provincial Hospital

81453381@qq.com+86 18753157303

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026