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Study on the metabolomics of the type of Spleen - Kidney Yang deficiency functional Diarrhea and the Intervention mechanism of Yu -Lao Jiu Xie Fang

Study on the metabolomics of the type of Spleen - Kidney Yang deficiency functional Diarrhea and the Intervention mechanism of Yu -Lao Jiu Xie Fang

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014306
Enrollment
Unknown
Registered
2018-01-05
Start date
2017-09-20
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional diarrhea

Interventions

healthy control group:?????

Sponsors

Second Affiliated Hospital of Guangzhou University of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic standard of functional diarrhea in western medicine; (2) accord with the type of spleen-kidney yang deficiency of TCM; (3) who are aged 18 or older but less than or equal to 65; (4) there were no take laxative, gastrointestinal excitomotor or other drugs that might cause diarrhea in the six months before being observed; (5) voluntary participate in clinical study and take the drugs as required.

Exclusion criteria

Exclusion criteria: (1) It was confirmed by the examination(such as colonoscopy, CT) that diarrhea caused by gastrointestinal organic diseases (such as tumor, inflammatory bowel disease,colonic polyps,intestinal tuberculosis,chronic pancreatitis,etc.); Or the systemic diseases which affect the digestive tract motion(such as hyperthyroidism,diabetes mellitus,CRF,etc.); (2) serious diseases of the heart,brain,liver,kidney,respiratory,endocrine system,hematopoietic system; (3) who was less than the age of 18 or older than 65; pregnancy or breast-feeding women; (4) Can not cooperate with the treatment because of psychosis or psychoneurosis; (5) allergic constitution or have been allergic to many Chinese medicine.

Design outcomes

Primary

MeasureTime frame
functional diarrhea disease symptom severity improvement;36-items shortform health survey;Saliva pH value;Biochemical indexes of saliva;Determination of saliva metabolites by 1H-NMR;

Countries

China

Contacts

Public ContactLi Jianhua

Second Affiliated Hospital of Guangzhou University of TCM

2351685325@qq.com+86 13533274606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026