The correlation of lung injury indexes in exhaled breath condensate and serum during the anesthesia of open heart surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800014299

Enrollment

Unknown

Registered

2018-01-04

Start date

2018-01-15

Completion date

Unknown

Last updated

2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

open heart surgery

Interventions

Ulinastatin Group:Use Ulinastatin

Control Group:Use NS

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients scheduled for cardiopulmonary bypass during open heart surgery will be enrolled in this study.

Exclusion criteria

Exclusion criteria: With a history of significant renal, hepatic, neurological and pulmonary inflammatory disease, recent use of antiinflammatory or antioxidation drugs, long term use of glucocorticoidor or immunodepressant.

Design outcomes

Primary

Measure	Time frame
Concentration of TNF-a;Concentration of IL-6;Concentration of IL-8;Concentration of 8-isoPG F2a;Concentration of H2O2;Results of Blood Gas Analysis;Occurrence of ALI;	—

Secondary

Measure	Time frame
extubation time;Duration of ICU;Discharge Time;Other Complications;	—

Countries

China

Contacts

Public ContactJie Song

The Second Affiliated Hospital of Nantong University

songjie1004@sina.com+86 13806298162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026