coronary heart disease
Conditions
Interventions
Two groups:Placebo and experimental medications
Sponsors
Guangdong General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) voluntarily participate in the trail, signed informed consent; 2) Complies with diagnostic criteria for coronary heart disease (including stable angina pectoris, unstable angina pectoris, non-ST-elevation myocardial infarction, acute ST-segment elevation myocardial infarction) required and completed as required percutaneous coronary intervention (PCI) Surgical patients; 3) PHQ-9 score 5-14 points, or GAD-7 score 5-14 points; 4) women of childbearing age must be treated before the urine pregnancy test and the results were negative, and not in lactation; 5) Aged 18-75 years male or female; 6) can cooperate with the inspection, treatment; 7) Patients have the ability to understand and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1) cachexia state; or combined lung, liver, kidney, hematopoietic system, the immune system and other serious primary disease and dysfunction; 2) angina pectoris did not relieve or NYHA cardiac function grade IV; 3) recurrent anxiety, depression patients 4) electrolyte imbalance acid-base imbalance; 5) history of epilepsy, or patients with organic mental disorders; 6) other mental illness such as: bipolar affective disorder, schizophrenia and other patients; 7) alcohol and drug abuse and drug addicts within one year; 8) other antidepressant and anxiolytic drugs were taken within four weeks before the test; 9) Pregnant or lactating women, or planned pregnancy; 10) had previous coronary revascularization; 11) participated in other drug clinical trials within 3 months; 12) Researchers believe that they are not suitable for clinical trials; 13) patients with cognitive impairment; 14) patients with suicidal tendencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the symptom of anxiety and depression;heart rate variety; | — |
Countries
China
Contacts
Public ContactQingshan Geng
Guangdong General Hospital
Outcome results
None listed