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Efficaay of microneedling plus mixed growth factors solutions derived from human mesenchymal stem cell for chloasma

Efficacy of microneedling plus mixed growth factors solutions derived from human mesenchymal stem cell for chloasma: a Randomized, Controlled, Blinded Split-Fcae Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014246
Enrollment
Unknown
Registered
2018-01-01
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chloasma

Interventions

Two groups:microneedling versus microneedling plus mixed growth factors solutions

Sponsors

Beijing Friendship Hospital affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 30-60 years old male and female; 2. 2 deputy chief physician diagnosed chloasma; 3. Facial skin intact, no obvious inflammation, ulceration, exudation; 4. No facial filler such as hyaluronic acid or laser/light treatment; 5. No oral steroids, collagen powder/liquid, or topical hyaluronic acid used in the last 3 months; 6. No skin whitening products in the last 2 weeks.

Exclusion criteria

Exclusion criteria: 1. Pregnant or in breast-feeding peroid; 2. Facial dermatitis patients; 3. Allergic to trial medcine or its ingredient; 4. Have severe cardiovascular, cerebrovascular, renal, hepatic or hematopoietic disease; 5. Poor coagulation function; 6. Taking part in other clinical trials; 7. People that researchers believe they are not suitable to participate in the study.

Design outcomes

Primary

MeasureTime frame
skin pores;skin texture;skin wrinkle;UV spots;Black brown spots;Erythema;skin hydration;skin transepidermal water loss;skin elasticity;skin melanin index;

Countries

China

Contacts

Public ContactZhuo Fenglin

Beijing Friendship Hospital affiliated to Capital Medical University

zflsunny@hotmail.com+86 15910895068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026