FindTrial
Sign In

Effect of curcuminoids on the blood level of digoxin in healthy male volunteers

Effect of curcuminoids on P-glycoprotein activity in healthy male subjects using digoxin as a probe

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TTRCC-14004645
Enrollment
Unknown
Registered
2014-05-14
Start date
2014-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Healthy males 2. Aged 20 – 30 years 3. No underlying disease or any history of clinically significant cardiovascular, respiratory, gastrointestinal, neurological and renal diseases4. The body mass index (BMI) within 18 – 25 kg/m2

Exclusion criteria

Exclusion criteria: 1. A significant abnormal electrocardiographic (ECG) finding 2. A resting heart rate less than 60 beats/min at screening 3. Significant abnormal complete blood count, serum electrolyte, serum creatinine levels, and thyroid function test 4. Recent cigarette smoking or alcohol drinking 5. Use of any other medication within 2 weeks before study participation 6. Consumption of any curcumin-rich foods such as curry within 1 week before study participation.

Design outcomes

Primary

MeasureTime frame
The difference on blood level of digoxi;—

Countries

Thailand

Contacts

Public ContactNutthiya Hanprasertpong
knutthiya@gmail.com+66-53-945-353

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026