Postmenopausal Women
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A total of 12 postmenopausal women, age > 45 y, postmenopausal status > 1 y since the last spontaneous menstrual bleeding and serum follicle-stimulating hormone concentration > 30 IU/L, will be enrolled in this study. The body mass index (BMI) of subjects must be within 18-25 kg/m2. All must be in good health on the basis of medical history, physical examination and routine blood test. Routine blood test including complete blood count (CBC) with differential, blood urea nitrogen (BUN), creatinine (Cr) and liver function test (LFT) will be screened to exclude subject with abnormal hematological diseases, abnormal liver or kidney functions.
Exclusion criteria
Exclusion criteria: Subjects who will be excluded are those with known history of chronic renal, liver, pulmonary, cardiovascular or gastrointestinal diseases, lactase deficiency, recent cigarette smoking or alcoholic consumption, a history of substance abuse or addiction, use of antibiotics, laxatives and other medications within the previous 4 wk. Intake of nutritional supplements containing vitamins, minerals, fibers, inulin, isoflavones, cow milk products, other prebiotics, probiotics or synbiotics within the previous 2 wk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma isoflavones level; | — |
Countries
Thailand