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Influence of Synbiotics Lactobacillus paracasei and Inulin on Pharmacokinetics of Isoflavones in Thai Healthy Postmenopausal Women

Influence of Synbiotics Lactobacillus paracasei and Inulin on Pharmacokinetics of Isoflavones in Thai Healthy Postmenopausal Women

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TTRCC-13003079
Enrollment
Unknown
Registered
2013-02-28
Start date
2013-03-07
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postmenopausal Women

Interventions

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
46 Years to No maximum

Inclusion criteria

Inclusion criteria: A total of 12 postmenopausal women, age > 45 y, postmenopausal status > 1 y since the last spontaneous menstrual bleeding and serum follicle-stimulating hormone concentration > 30 IU/L, will be enrolled in this study. The body mass index (BMI) of subjects must be within 18-25 kg/m2. All must be in good health on the basis of medical history, physical examination and routine blood test. Routine blood test including complete blood count (CBC) with differential, blood urea nitrogen (BUN), creatinine (Cr) and liver function test (LFT) will be screened to exclude subject with abnormal hematological diseases, abnormal liver or kidney functions.

Exclusion criteria

Exclusion criteria: Subjects who will be excluded are those with known history of chronic renal, liver, pulmonary, cardiovascular or gastrointestinal diseases, lactase deficiency, recent cigarette smoking or alcoholic consumption, a history of substance abuse or addiction, use of antibiotics, laxatives and other medications within the previous 4 wk. Intake of nutritional supplements containing vitamins, minerals, fibers, inulin, isoflavones, cow milk products, other prebiotics, probiotics or synbiotics within the previous 2 wk.

Design outcomes

Primary

MeasureTime frame
Plasma isoflavones level;

Countries

Thailand

Contacts

Public ContactAssoc. Prof. Dr. Supanimit Teekachunhatean
steekach@med.cmu.ac.th+66 053945353

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026