Healthy volunteers
Conditions
Interventions
group 1:administrated with simvastatin and Ginkgo biloba extract
group 2:administrated with simvastatin
Sponsors
Institute of Clinical Pharmacology, Central South University
Eligibility
Sex/Gender
Male
Age
19 Years to 25 Years
Inclusion criteria
Inclusion criteria: Male, 19-25 years of age (including boundary value); subjects body mass index (BMI): 19-25 Male, 19-25 years of age (including boundary value); subjects body mass index (BMI): 19-25 (including boundary value); According to the medical examination, vital signs, electrocardiogram and clinical laboratory result, participants are healthy, and the inspection was taken 1 week before the drug administration; subjects are able to read and understand the contents of the informed consent, and sign the informed consent before any research related operations; subjects are not taken any other drugs two weeks before the test.
Exclusion criteria
Exclusion criteria: Subjects with arrhythmia, bronchial or cardiovascular disease history, diabetes, thyrotoxicosis, Parkinson's syndrome, or any other disease or physiology that can interference test results; with disease that can affect drug absorption or metabolic disease of the gastrointestinal tract; have drug abuse history or positive urine drug test results in the past five years; used other medicines within 14 days before the test; participated in other drug experiments within 30 days before the test; Serious blood loss or donation (500 ml) within 30 days before the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood drug concentration; | — |
Countries
China
Contacts
Public ContactHong-Hao Zhou, Lan Fan
Outcome results
None listed