immunosuppression
Conditions
Interventions
J:Oral 6mg the reference tablets
y:Oral 2mg the test tablets
Sponsors
First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
Male
Age
20 Years to 27 Years
Inclusion criteria
Inclusion criteria: 1. Male, Aged from 18 to 40 years old, no more than 10 years in age difference of thee subjects in the same group; 2. BMI ranged from 19 to 25 kg/m2; 3. No history of organic disease and drugallergy; 4. Subjects with normal findings as determined by baseline history, physical examination, vital signs, Haemogram with ESR, Biochemistry, Infectious Disease Screening (HIV, Hepatitis B and Hepatitis C) and Urinalysis, ECG; 5. No drug abuser; 6. No alcoholic and smoking addiction; 7. Good communication with researchers and complied for requirements during the whole research work; 8. given a written informed- consent form and sign on the ICF.
Exclusion criteria
Exclusion criteria: 1. Participated in other clinical research within 3 months; 2. Had a history of blood donation within 1 month or intended to donate blood during the trial; 3. Failed in the general examination, blood pressure, heart rate and breath condition; 4. Any obvious clinical symptoms of disease founded during the medical examination; 5. laboratory evidence of hematology renal cardiac and hepatic abnormity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The blood concentrations of sirolimus; | — |
Countries
China
Contacts
Public ContactJianzhong Shen-Tu
First Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed