Pretreatment with a bolus Intravenous Lipid Infusion Influences the Pharmacodynamics Pharmacokin
Conditions
Interventions
lipid emulsion Group:Intravenous lipid emulsion
Sponsors
Longyan No. 1 Hospital, affiliated with Fujian Medical University, Fujian, China.
Eligibility
Sex/Gender
Male
Age
30 Years to 62 Years
Inclusion criteria
Inclusion criteria: Unilateral lower limb operation patients
Exclusion criteria
Exclusion criteria: patient reful, age younger than 18 year, weight less than 50 kg, ASA class more than 3, anticoagulant treatment, neurologic or neuromuscular disease, hepatic disorders, renal disorders, hemorrhagic necrosis pancreatitis, disorders of lipid metabolism, electrolyte imbalance, pregnant woman, or patients unlikely to be fully cooperative during the study, such as those with neurological or psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma total levobupivacaine concentration;plasma free levobupivacine concentration;Triglyceride concentration;Sensory onset time;Sensory recovery tim; | — |
Countries
China
Contacts
Public ContactChen Ying
Outcome results
None listed