Immediate-release morphine in combination with sustained-release morphine as a novel titration for cancer pain

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14005118

Enrollment

Unknown

Registered

2014-08-14

Start date

2014-08-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer pain

Interventions

Study group:Immediate-release morphine in combination with sus

Contral group:standard Immediate-release morphine titration

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Malignant tumor patients with cancer pain, and without experience of opium medication; 2. NRS evaluation reaching 4-10; 3. 18 years old and upward; 4. No obvious abnormality in key organs;(Reference to the chemo treatment standard); 5. Informed consent from the patient and his/her family; 6. The patient is clearly conscious, not disabled from language, no mental retardation, able to understand, speak and write.

Exclusion criteria

Exclusion criteria: 1. With other serious diseases; 2. With experience of opium medicines abuse, or mental disorder; 3. In pregnancy or nursing; 4. Sensitive to opium medicines; Oral tablet can not be administred; 5. Using other medicines specifically for pain killing reason or under other pain killing treatment.

Design outcomes

Primary

Measure	Time frame
Number of times the immediate-release morphine injection as saving treatment during begaining of titration till pain-contral background constructed;	—

Secondary

Measure	Time frame
time to pain released;	—

Countries

China

Contacts

Public ContactJiang Zhu, Junying Li

zhujiang1@medmail.com.cn+86 18980602256, 18980601764

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026