Periodontitis
Conditions
Interventions
3 groups:Periodental non-surgical treatment
Sponsors
Stomatology Hospital of Guangdong Province
Eligibility
Sex/Gender
Male
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pre-diabetes with OGTT (2hPG) more than 7.8 to 11.1mmol/L (more than 140 to 200mg/dl); 2. Accord with the diagnosis standard of moderately severe periodontitis; 3. Participates are over 35 and have informed consent in this project; 4. Have the ability and willingness to comply with the study protocol, practice on every appointment requirements; 5. Without history of periodontal treatment in 6 months before baseline; 6. Have at least 16 natural tooth during the study; 7. Avoid pregnancy during the study.
Exclusion criteria
Exclusion criteria: 1. Have serious disease, and have less than 1 year life expectancy by specialized doctor; 2. Intermittent or continuous use of non-steroidal anti-inflammatory drugs in 2 months before the baseline (once a day, more than 7 days), except for the low-dose aspirin (75-325 mg a day, for example); 3. Undergoing systemic corticosteroids, cyclosporine or other chronic systemic immune system suppression drugs treatment; 4. Undergoing a chronic systemic antimicrobial drug treatment(use more than 6 days within the 30 days prior to baseline); 5. Undergoing dialysis; 6. History indicates a risk of hemorrhagic complication related to dental treatment; 7. Undergonig dental treatment which is unable to delay (such as tooth decay, cracked tooth, tooth source sex abscess, apical infection, or other tooth infection); 8. Alcoholics (women drink 2 times a day, men drink 3 times a day); 9. Pregnants or plan to become pregnant in 6 months; 10. Participants who are adverse to the study or any condition adverse to the study; 11. Have tooth etraction in periodontal treatment during the study period; 12. Smokers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glycosylated hemoglobin;insulin; | — |
Countries
China
Contacts
Public ContactZhang Jincai
Outcome results
None listed