traumatic optic neuropathy
Conditions
Interventions
control group:normal saline with 1% human serum albumin
Sponsors
Cell Biotherapy Center, Daping Hospital, The Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Good adherence to patients and their families with informed consents; 2. patients of ophthalmology, aged from 16 to 65 years old, both gender; 3. Clinical diagnosis of patients with traumatic optic neuropathy; 4. Injury time within 1 month with stable vital signs; 5. The wounded eye's best corrected vision less than or equal to 0.3; 6. The wounded eye without penetrating wound and fracture wound, refractive stroma transparent.
Exclusion criteria
Exclusion criteria: 1. Intracranial bleeding due to trauma, traumatic brain injury and other vital signs is not steady, or accompany with heart, lung disease, or severe liver and kidney function; 2. The wounded eyes with severe ocular blunt trauma:detached peripheral iris, lens dislocation, ciliary body detachment or laceration, vitreous hemorrhage, retinal detachment, retina and choroid laceration, etc; 3. HIV infected with CD4 less than 50/mm3; 4. Have the bone marrow, lungs, liver, pancreas, or history of small bowel transplantation; 5. Chronic renal failure need hemodialysis or peritoneal dialysis; 6. Accompany with high surgical risk diseases, such as sphenoid sinus dysplasia, cerebrospinal fluid rhinorrhea, internal carotid artery dissection aneurysm, etc; 7. Patient participating or having participated in a clinical trial with another investigational drug Within 30 days before the start of this clinical trial; 8. Patient is pregnant or nursing; 9. History of patient is allergic to biological products, allergic reactions or other serious reaction; 10. Researchers believe that patients cannot participate in this clinical trail for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vision;view;VEP; | — |
Countries
China
Contacts
Public ContactXiang Xu
Outcome results
None listed