periodontal disease
Conditions
Interventions
Treatment group:non-surgical periodontal treatment
Control group:No intervention
Sponsors
Department of Stomatology, Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
39 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. adults more than 30 years old; 2. All ESRD patients had been undergoing on average 4 h of HD 3 times/wk. All HD patients had a stable status, in the previous two months and with no major complication; 3. a clinical diagnosis of moderate generalized chronic periodontitis (Armitage 1999), presence of more than 16 teeth in the mouth, excluding third molars; 4. had no systemic antibiotic administration within the previous 3 months; 5. and no previous periodontal treatment.
Exclusion criteria
Exclusion criteria: 1. the presence of a systemic disease including diabetes that could influence the course of the periodontal disease; 2. systemic antibiotic administration within the previous 3 months; 3. pregnancy or lactation; 4. an active infection other than periodontitis or had received periodontal treatment in the previous 12 months; 5. Taking medicines influcing the systemic inflammation; 6. hemodialysis treatment less than 6 months; 7. hospitalization, surgery, or renal transplantation within the preceding 3 months; 8. refusal to provide written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRP; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-alpha;IL-6;ferritin;Alb;BUN;Cr;ALC;Tf;nPCR;TC;TG;HDL-C;LDL-C; | — |
Countries
China
Contacts
Public ContactFuchun Fang
Outcome results
None listed