The effect of dehydroepiandrosterone plus climen supplementation for patients with diminished ovarian reserve

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14005030

Enrollment

Unknown

Registered

2014-07-30

Start date

2014-08-05

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diminished ovarian reserve

Interventions

DHEA+Climen group:DHEA 75mg+climen 1mg daily for two months

DHEA group:DHEA DHEA 75 mg daily for two months

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. an elevated day 3 FSH level more than 10 mIU/mL or FSH/LH more than 3; 2. the number of antral follicle count less than five; 3. a previous poor ovarian response: retrieval of fewer than five oocytes or cycle cancellation due to poor response to ovarian stimulation. A diagnosed with DOR was reached if they fulfill any of the above three features.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had any of the following: 1. a history of ovarian cystectomy or oophorectomy; 2. a diagnosis of endometriosis; 3. a history of DHEA supplementation or hormonal replacement therapy.

Design outcomes

Primary

Measure	Time frame
AMH;FSH;E2;	—

Countries

China

Contacts

Public ContactZhaolian Wei

weizhaolian_1@126.com+86 13865916162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026