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Research of parecoxib sodium to prevent activity pain after Hepatobiliary and pancreatic laparotomy

Research of parecoxib sodium to prevent activity pain after Hepatobiliary and pancreatic laparotomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004991
Enrollment
Unknown
Registered
2014-05-21
Start date
2014-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Activities pain after Hepatobiliary and pancreatic laparotomy

Interventions

Experimental group:Postoperative analgesia pump + intravenous parecoxib sodium analgesic
placebo group:Postoperative analgesia pump + intravenous NS
Control group:just analgesia pump

Sponsors

Third Affiliated Hospital of Third Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years, ASA I or II, without understanding disorders; 2. Open abdominal surgery, surgical incisions more than 10cm; 3. Patients signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Suffering from severe heart disease, brain disease, liver disease, kidney disease, severe somatic diseases; 2. Patients with mental or neurological diseases; 3. Drug abuse, alcoholic beverages or drug users; 4. Patients should underwent secondary surgery; 5. With a history of chronic pain patients; 6. Not taking over the non-steroidal anti-inflammatory drugs (NSAIDs), or narcotic analgesics within the past three months; 7. Pregnancy, breast-feeding women; 8. With severe immune dysfunction.

Design outcomes

Primary

MeasureTime frame
VAS after activity;Use the number of PCA;VAS;

Secondary

MeasureTime frame
Complication;Postoperative hospital stay;Gastrointestinal function recovery time;Surgical incision, Length;

Countries

China

Contacts

Public ContactLiu Menggang
menggang_liu@hotmail.com+86 13228687389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026