The study of the clearances of solutes by a novel mode of continuous renal replacement therapy

The clearances of solutes by a novel mode of continuous renal replacement therapy: a prospective randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004985

Enrollment

Unknown

Registered

2014-07-22

Start date

2014-07-22

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury

Interventions

DF-HDF Group:DF-HDF

SVHF Group:standard CVVH

HVHF Group:HVHF

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) patients aged 18-70; (2) patients complicated with systemic inflammation syndrome and acute kidney injury requiring continuous replacement therapy; (3) Having signed infrom consent.

Exclusion criteria

Exclusion criteria: (1) patients with advanced cirrhosis, advanced tumor or decompensated heart failure; (2) pregnant woman; (3) history of allergy to extrocorporeal circuit; (4) contraindication of extracorporeal circuit; (5) contraindication of systemic anticoagulation; (6) blood flow less than 180ml/min; (7) severe hypoalbumina (serum albumin less than 25g/L); (8) weight more than 90 kilogram; (9)hemocrit more than 0.4.

Design outcomes

Primary

Measure	Time frame
clearance of IL-1;	—

Secondary

Measure	Time frame
clearance of Scr;clearance of amino acids;clearance of ferin;clearance of folic aci;	—

Countries

China

Contacts

Public ContactGong Dehua

gong_doctor@126.com+86 15951880053

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026