myopia
Conditions
Interventions
Left vs right:Four concentration of atropine: atropine eye drops on right eyes while atropine eye ointment on left eyes
Sponsors
Beijing Tongren Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 26 Years
Inclusion criteria
Inclusion criteria: 1. Written Informed Consent from them and verbal assent from them has been obtained; 2. Teenagers aged 20 to 26years; 3. Spherical equivalent -1.00D or worse in each eye as measured by cycloplegic autorefraction; 4. Astigmatism less than -1.50 D as measured by cycloplegic or non-cycloplegic autorefraction; 5. Distance vision correctable to logMAR 0.2 or better in both eyes; 6. A difference between non-cycloplegic subjective spherical refraction and cycloplegic subjective spherical refraction of not greater than -1.00 D; 7. Normal intraocular pressure of not greater than 21 mmHg; 8. Normal ocular health other than myopia; 9. In good general health with no history of cardiac or significant respiratory diseases; 10. No regular use of asthma-requiring medications in the past one year as determined by investigator; 11. No allergy to atropine, cyclopentolate, proparacaine and benzalkonium chloride; 12. Willing and able to comply with scheduled visits and other study procedures.
Exclusion criteria
Exclusion criteria: 1. Ocular or systemic diseases which may affect vision or refractive error; 2. Any ocular condition where in topical atropine is contraindicated; 3. Defective binocular function or stereopsis; 4. Amblyopia or manifest strabismus including intermittent tropia; 5. Conditions precluding adherence to the protocol including unwillingness to refrain from contact lens wear for the duration of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Refractive errors;Pupil size;Accommodation;near vision;LogMAR visual acuit; | — |
Countries
China
Contacts
Public ContactWang Ningli
Outcome results
None listed